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EXCEL FIND DUPLICATES MCAC TRIAL

This in turn will facilitate a deeper understanding of how human biological systems and molecular pathways interact with or mediate the relationships among dietary patterns, environmental, social, and behavioral factors to influence health status. Research is needed to provide more precise and dynamic nutritional recommendations than currently possible through population-wide guidance. The Plan was organized around a unifying vision of precision nutrition research. The 2020-2030 Strategic Plan for NIH Nutrition Research was released in 2020 and will guide NIH-supported nutrition research over the next decade. Strategic plan for NIH Nutrition Research MCAC: Metabolomics and Clinical Assays Center.The set of six companion FOAs and existing All of Us Research Program components will establish the Nutrition for Precision Health consortium. The Overall study coordination and data management (this FOA) will be provided by a Research Coordinating Center (RCC).

EXCEL FIND DUPLICATES MCAC TRIAL

RFA-RM-21-006: Nutrition for Precision Health, powered by the All of Us Research Program: Research Coordinating Center (U24 Clinical Trial Not Allowed).

Clinical Centers will engage, consent, and enroll participants from All of Us and conduct 3 diet modules (usual dietary assessment, a controlled feeding dietary intervention and a domiciled dietary intervention).

RFA-RM-21-005: Nutrition for Precision Health, powered by the All of Us Research Program: Clinical Centers (UG1 Clinical Trial Required).

A Dietary Assessment Center will conduct dietary assessment on participants and develop innovative approaches to address dietary assessment challenges.

RFA-RM-21-004: Nutrition for Precision Health, powered by the All of Us Research Program: Dietary Assessment Center (U24 Clinical Trial Optional).

A Microbiome and Metagenomics Center will perform microbiome, metagenomics and metatranscriptomics analyses on stool samples for all participants.

RFA-RM-21-003: Nutrition for Precision Health, powered by the All of Us Research Program: Microbiome and Metagenomics Center (U24 Clinical Trial Not Allowed).

An Artificial Intelligence, Multimodal Data Modeling, and Bioinformatics Center will develop comprehensive dietary intervention algorithms that can predict biological responses.

RFA-RM-21-001: Nutrition for Precision Health, powered by the All of Us Research Program: Artificial Intelligence for Multimodal Data Modeling and Bioinformatics Center (U54 Clinical Trial Not Allowed).All Common Fund initiatives invite investigators to develop bold, innovative, and often risky approaches to address problems that may seem intractable or to seize new opportunities that offer the potential for rapid progress.Īpplicants responding to this FOA are expected to familiarize themselves with the five other companion FOAs listed below since the MCAC will be expected to communicate, coordinate, and collaborate with the awarded components of these FOAs.Ĭompanion FOAs of the Nutrition for Precision Health Consortium This initiative is funded through the NIH Common Fund, which supports cross-cutting programs that are expected to have exceptionally high impact. The focus of this center is to (1) generate targeted and non-targeted metabolite profiles and (2) perform or facilitate clinical assays from blood, urine and stool biospecimens. The purpose of Announcement (FOA) is to solicit applications for the Metabolomics and Clinical Assays Center (MCAC) to join the Nutrition for Precision Health Consortium.